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Cells were blocked with 5% BSA in PBS and incubated with primary antibodies overnight
Foam cell formation: a new target for fighting atherosclerosis and cardiovascular disease
Pro-inflammatory and proatherogenic mCRP, but not nCRP, induces ROS monocyte/macrophage production and facilitates macrophage uptake of necrotic cells (170, 192) contributing to foam cell formation, atherosclerotic plaque formation and plaque rupture or destabilization (190, 191)
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however, several mechanisms have been proposed
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